Advancing AI’s Sense of Smell

Scientists are undertaking the challenge of training AI to recognize and describe odors, revealing the intricate nature of this task even for advanced computers.

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The sense of smell is amazing! Research shows that humans can tell apart more than a trillion different smells. Each smell is like a special chemical with its own design. Smart people are trying to figure out if there are rules or patterns that explain why chemicals smell the way they do.

If they can crack this code, it’ll be simpler to make artificial scents or find new ones. But it’s really hard because two chemicals that look similar can have totally different smells. So, scientists are wondering: Can we teach a computer to do this tricky job?

Smell is a mystery to scientists, unlike our ability to understand sight and hearing. We can describe what we see in terms of light wavelengths and what we hear in terms of sound waves, but smell remains uncharted territory. In recent research featured in the journal Science, scientists used a neural network to teach a computer about 5,000 compounds from perfume databases.

These compounds are molecules that have distinct smells, like “fruity” or “cheesy.” The AI created a “principal odor map” that visually represented how different smells relate to each other. When the scientists introduced a new molecule to the AI, it could predict what it would smell like in descriptive terms.

The research team went a step further by having 15 adults from diverse racial backgrounds in the Philadelphia area smell and describe the same odor. What they discovered was that, most of the time, the AI’s descriptions were more accurate than those of the average panelist.

Alex Wiltschko, one of the authors of the study and the CEO and co-founder of Osmo, a company dedicated to giving computers a sense of smell, emphasized this achievement. Osmo collaborated with researchers from Google and several US universities on this groundbreaking research.

“Scent is a very personal experience,” notes Sandeep Robert Datta, a neurobiology professor at Harvard University. While Datta has advised Osmo in the past, he wasn’t involved in this latest study. He highlights that any research concerning how we describe and categorize odors must consider that our perception of scents and their relationships is closely tied to our memories and culture.

This complexity makes it challenging to determine what the “best” way to describe a smell is. Nevertheless, Datta explains that there are shared aspects of scent perception, likely driven by chemistry, and that’s precisely what this odor map aims to capture.

It’s worth highlighting that this research team isn’t the pioneering or sole group using computer models to explore the connection between chemistry and our perception of smell, as Datta points out. There are other neural networks and various statistical models that have been trained to correlate chemical structures with scents.

However, the notable achievement here is that this new AI generated an odor map and demonstrated the ability to forecast the scents of previously unknown molecules, which holds significant importance, according to Datta.

The study’s breakthrough in teaching AI to understand and describe smells is a significant advancement in our understanding of scent perception. While scent is highly personal and influenced by individual memories and culture, this AI-driven approach has managed to capture common aspects of smell perception rooted in chemistry.

The ability of the AI to produce an odor map and predict the scents of new molecules is a noteworthy achievement, even though it is not the first of its kind. This research opens up exciting possibilities for various applications, from fragrance design to potential advancements in fields like healthcare and environmental monitoring.

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